JAPANESE JOURNAL OF CLINICAL ONCOLOGY

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JAPANESE JOURNAL OF CLINICAL ONCOLOGY Vol. 42 No. 10

October 2012

CONTENTS Review Articles 867

Cancer Control in the Asia Pacific Region: Current Status and Concerns Hai-Rim Shin, Marie Clem Carlos and Cherian Varghese This paper reviews the cancer burden, prevalence of main modifiable risk factors and status of cancer control programmes in countries in the Asia Pacific Region, which is projected to have the greatest total number of deaths due to noncommunicable diseases in 2020.

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Research Trends of Oncology Nursing in Japan and Around the World Atsuko Uchinuno This article reviews recent cancer nursing research in Japan and the United States, and topics relating to international cancer nursing societies.

Original Articles Central Nervous System 887

Phase II Study of Single-agent Bevacizumab in Japanese Patients with Recurrent Malignant Glioma Motoo Nagane, Ryo Nishikawa, Yoshitaka Narita, Hiroyuki Kobayashi, Shingo Takano, Nobusada Shinoura, Tomokazu Aoki, Kazuhiko Sugiyama, Junichi Kuratsu, Yoshihiro Muragaki, Yutaka Sawamura and Masao Matsutani We describe an open-label study of single-agent bevacizumab, which demonstrated clinical benefit with an acceptable safety profile in Japanese patients with recurrent glioblastoma.

Clinical Trials 896

Evaluation of Three Definitions of Progression-free Survival in Preoperative Cancer Therapy (JCOG0801-A) Kenichi Nakamura, Taro Shibata, Atsuo Takashima, Seiichiro Yamamoto and Haruhiko Fukuda There are three typical definitions of progression-free survival in trials evaluating preoperative therapy. Progression-free survival using each definition sometimes fails as a surrogate of overall survival.

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Everolimus for Advanced Pancreatic Neuroendocrine Tumours: A Subgroup Analysis Evaluating Japanese Patients in the RADIANT-3 Trial Tetsuhide Ito, Takuji Okusaka, Masafumi Ikeda, Hisato Igarashi, Chigusa Morizane, Kohei Nakachi, Takeshi Tajima, Akio Kasuga, Yoshie Fujita and Junji Furuse Everolimus had even greater clinical benefit and prolonged progression-free survival in the 40 Japanese patients with pancreatic neuroendocrine tumors enrolled in RADIANT-3 than the overall population.

Diagnostic Radiology 912

Prediction of Treatment Outcomes in Patients with Chest Wall Sarcoma: Evaluation with PET/CT Yuji Nishiyama, Ukihide Tateishi, Akira Kawai, Hirokazu Chuman, Fumihiko Nakatani, Mototaka Miyake, Takashi Terauchi, Tomio Inoue and Edmund E. Kim Positron emission tomography/computed tomography allows prediction of prognosis after treatment in patients with chest wall sarcoma and may be useful in selecting high-risk patients for more risk-adapted treatments.

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Epidemiology/Public Health 919

Discrepancies Between Public Perceptions and Epidemiological Facts Regarding Cancer Prognosis and Incidence in Japan: An Internet Survey Miyako Takahashi, Ichiro Kai and Takashi Muto An Internet survey involving 2369 Japanese people revealed wide discrepancies between public perceptions and epidemiological data for both cancer prognosis and lifetime incidence.

Head & Neck 927

Phase II Feasibility Trial of Adjuvant Chemoradiotherapy with 3-weekly Cisplatin for Japanese Patients with Post-operative High-risk Squamous Cell Carcinoma of the Head and Neck Naomi Kiyota, Makoto Tahara, Susumu Okano, Mitsuhiko Kawashima, Kazuto Matsuura, Yuske Onozawa, Kenichi Nibu, Ryuichi Hayashi, Kenichi Yoshimura and Atsushi Ohtsu Safety and compliance of adjuvant chemoradiotherapy with 3-weekly cisplatin chemotherapy for postoperative high-risk squamous cell carcinoma of the head and neck in a Japanese population appears to be equivalent to that reported previously.

Other Specialties 934

Referral-free Health Care and Delay in Diagnosis for Lung Cancer Patients Vivian Chia-Rong Hsieh, Trong-Neng Wu, Shu-Hui Liu and Shwn-Huey Shieh Reducing the number of hospitals visited before diagnosis for lung cancer can prevent wasteful medical resources and decrease the delay in diagnosis.

Psycho-Oncology 940

Association of Coping Style, Cognitive Errors and Cancer-related Variables with Depression in Women Treated for Breast Cancer Nilufer Alcalar, Sedat Ozkan, Seden Kucucuk, Isik Aslay and Mine Ozkan Results show that a causal relationship exists between depression and a patient’s cognitive patterns and accompanying anxiety. Depression is inversely related to both fighting spirit coping type and educational level.

Radiation Oncology 948

Comparison of Treatment Outcomes Between Involved-field and Elective Nodal Irradiation in Limited-stage Small Cell Lung Cancer Tae Jin Han, Hak Jae Kim, Hong-Gyun Wu, Dae-Seog Heo, Young Whan Kim and Se-Hoon Lee This retrospective study of limited-stage small cell lung cancer demonstrated that involved-field irradiation without positron emission tomography-based staging resulted in impaired survival outcomes and raised the risk of isolated nodal failure.

Urology 955

Utility of Inflammation-based Prognostic Scoring in Patients Given Systemic Chemotherapy First-line for Advanced Inoperable Bladder Cancer Eu Chang Hwang, In Sang Hwang, Ho Song Yu, Sun-Ouck Kim, Seung Il Jung, Jun Eul Hwang, Taek Won Kang, Dong Deuk Kwon, Kwangsung Park and Soo Bang Ryu A systemic inflammatory response coupled with hypoalbuminemia correlates significantly with a shortened overall survival and may thus be useful as a prognostic index for advanced inoperable bladder cancer.

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Case Reports 961

Hypomanic Episode During Recurrent Gastric Cancer Treatment: Report of a Rare Case and Literature Review Mototsugu Matsunaga, Hideki Onishi, Mayumi Ishida, Keisuke Miwa, Kazuhiro Araki, Toshikado Kaneta, Yu Sunakawa, Hirofumi Nakayama, Ken Shimada, Tsuyoshi Noguchi, Masaru Narabayashi and Yasutsuna Sasaki Gastric cancer patients undergoing chemotherapy may experience hypomania. Thus, it is important that clinicians recognize psychosis or mood disorders during gastric cancer treatment.

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A Case of Acute Exacerbation of Idiopathic Pulmonary Fibrosis After Proton Beam Therapy for Non-small Cell Lung Cancer Tatsuya Nagano, Yoshikazu Kotani, Osamu Fujii, Yusuke Demizu, Yasue Niwa, Yoshiharu Ohno, Wataru Nishio, Tomoo Itoh, Masao Murakami and Yoshihiro Nishimura The present case highlights acute exacerbation of idiopathic pulmonary fibrosis after proton beam therapy for non-small cell lung cancer in a patient with idiopathic pulmonary fibrosis, for the first time.

Clinical Trial Note 970

A Randomized Controlled Trial Comparing Primary Tumour Resection Plus Systemic Therapy With Systemic Therapy Alone in Metastatic Breast Cancer (PRIM-BC): Japan Clinical Oncology Group Study JCOG1017 Tadahiko Shien, Kenichi Nakamura, Taro Shibata, Takayuki Kinoshita, Kenjiro Aogi, Tomomi Fujisawa, Norikazu Masuda, Kenichi Inoue, Haruhiko Fukuda and Hiroji Iwata This trial designed by the Japan Clinical Oncology Group breast cancer group is being conducted to confirm the superiority of primary tumor resection plus systemic therapy over systemic therapy alone in patients with stage IV breast cancer.

Epidemiology Note 974

Trends in ‘Cure’ Fraction from Colorectal Cancer by Age and Tumour Stage Between 1975 and 2000, Using Population-based Data, Osaka, Japan Yuri Ito, Tomio Nakayama, Isao Miyashiro, Tomoyuki Sugimoto, Akiko Ioka, Hideaki Tsukuma, Manar E. Abdel-Rahman and Bernard Rachet From the late 1970s, the ‘cure’ fraction for colorectal cancer increased dramatically due to better management of detection and care for colorectal cancer in Osaka, Japan.

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Image of the Month and Cancer Statistics Digest

Contents of the Journal of the National Cancer Institute

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